Kolokvij: Pre-LUCA Protein Evolution: Lessons from Metabolism and Machine Learning

Zadovoljstvo nam je pozvati vas na zajednički kolokvij Kemijskog odsjeka Prirodoslovno-matematičkog fakulteta Sveučilišta u Zagrebu (PMF-KO) i HDBMB-a:

Kolokvij  će se održati 28.11.2025. u 12:15 sati u predavaonici P1, PMF-KO, Horvatovac 102A, Zagreb.

Predavač: Izv. prof. Liam M. Longo, Earth-Life Science Institute, Tokyo Institute of Technology, Japan

Naslov predavanja: Pre-LUCA Protein Evolution: Lessons from Metabolism and Machine Learning

Sažetak predavanja: “How can we reconstruct the earliest stages of protein evolution? In this talk, I will discuss two perspectives that can reveal pre-LUCA protein evolution – the web of enzyme requirements in metabolism and the centrality of a protein in sequence-structure space. On the basis of these data, I will argue that the history of protein emergence is knowable, even billions of years after the fact. Finally, I will use these perspectives to underscore one of the greatest mysteries in biology: The existence of two classes of aminoacyl-tRNA synthetases.”